The chiral title compound, C19H32O2, contains a [4.3.0]-bicyclic moiety in which the shared Toys C—C bond presents a trans configuration and a side chain in which the C=C double bond shows an E conformation.The conformations of five- and six-membered rings are envelope (with the bridgehead atom bearing the methyl substituent as the flap) and
In the city of Bobo-Dioulasso in Burkina Faso, Anopheles arabiensis has superseded Anopheles gambiae s.s.as the major malaria vector and the larvae are found in highly polluted habitats normally considered unsuitable for Anopheles mosquitoes.Here we show that An.gambiae s.l.adults emerging from a highly polluted site in the city centre (Dioulassoba
Targeting defects in metabolism is an underutilized strategy for the treatment of cancer.Arginine auxotrophy resulting from the silencing of argininosuccinate synthetase 1 (ASS1) is a common metabolic alteration reported in a broad range of aggressive cancers.To assess the metabolic effects that arise from acute and chronic arginine starvation in A